Job Openings

At Constellation all of our employees are committed to meeting the unmet medical needs of patients. We are passionate about our work and strive for scientific breakthroughs, viewing each day as an opportunity to learn from one another.  At Constellation we work hard and play hard. Whether it’s a charity bike race, family fun or getting together after work, we enjoy our colleagues’ company outside of the labs and meeting rooms. We believe that the key to a successful company are passionate, challenged, appreciated, and rewarded employees.


Current Openings

We are looking for the following full time positions to join our organization, contribute to an outstanding research, development and business team and be part of the next major product engine leveraging insights from the rapidly expanding field of chromatin biology to discover and develop small molecule therapeutics for the treatment of cancer, inflammatory/immunologic disorders and other diseases.

Senior Systems Engineer and Security Specialist

Constellation Pharmaceuticals is a pioneer epigenetics company, focused on the discovery and development of novel, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs.

We are growing our IT team and looking for an experienced and talented Systems Engineer and Security Specialist. Join us if you like to roll up your sleeves in a fast-paced environment where you get exposure to a wide variety of technical areas.

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Senior Desktop and Lab Support Engineer

Constellation Pharmaceuticals is a pioneer epigenetics company, focused on the discovery and development of novel, small molecules targeting chromatin regulatory proteins in tumor and immune cells for therapeutic applications in oncology. Our unique discovery platform integrates our understanding of chromatin-regulatory mechanisms with cancer and immune pathways to optimize our drug discovery activities and fully enable the clinical translation of our programs.

We are growing our IT team and looking for an experienced and talented Desktop Support Engineer who wants to add to their technical skills. Join us if you like to roll up your sleeves in a fast-paced environment where you get exposure to a wide variety of technical areas.

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Senior Scientist – Computational Chemistry

We are seeking a highly skilled and experienced computational chemist to join our team. Experience with ligand-based and protein-based drug design, scaffold morphing, conformational analysis, data handling and cheminformatics, HTS and biophysics data is desired. Knowledge of the various commercial modeling tools; concrete contributions as a member of successful multi-disciplinary teams; and an understanding of the key aspects of medicinal chemistry and drug discovery is also expected. This position includes the responsibility for the development and execution of the computational chemistry strategy across our drug discovery portfolio. The successful candidate will be flexible, independent, organized, detail oriented team player.

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Medical Director

We are adding to our Clinical Team and seeking a Medical Director with experience in successfully leading clinical programs in the oncology space.

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Clinical Trial Manager

Reporting to the Director of Clinical Operations, the successful candidate will be responsible for all aspects of clinical trial management from study start up through study closure.

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Clinical Scientist

We are adding to our Clinical Team and seeking a motivated and enthusiastic clinical scientist with experience in successfully executing on clinical programs in the oncology space.

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Development Project Management

The development project manager will have the opportunity to lead the strategic advancement of programs in the late pre-clinical, IND enabling and early development phases. In so doing, the manager will implement best development practices including project planning, budget and timeline creation and execution. The manager will integrate the input and efforts from multiple disciplines and with CRO partners and consultants, in addition to working collaboratively with senior leadership in research and clinical development to support the overall corporate strategic objectives.

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Scientist / Senior Scientist Pharmacology

We are seeking an experienced, accomplished and resourceful scientist with a successful track record in in vivo and in vitro pharmacology to join our research group. The role involves working closely with the project team leaders to design, execute and evaluate PK-PD and efficacy studies for lead compounds. The ideal candidate will have significant small molecule drug discovery experience in rodent pharmacology as demonstrated by scientific publications/ patents/ high impact projects. The successful applicant will be independent, organized, detail oriented, flexible, and will enjoy working in a dynamic, fast paced team environment.

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Biomarker Researcher

The Biomarker Researcher will be responsible for the implementation and interpretation of biomarkers in the clinical development of Constellation’s portfolio of novel compounds. The incumbent will guide the implementation and interpretation of biomarkers used to assess a compound’s pharmacodynamic effects in patients and of biomarkers used to guide the selection of patients most likely to benefit from treatment. S/He will be responsible for coordinating and managing biomarker work with external vendors and academic laboratories conducted on behalf of/in collaboration with Constellation. While this individual will be primarily responsible for biomarker implementation and interpretation in the clinic, s/he will work closely with Constellation’s research organization responsible for biomarker discovery and provide guidance regarding the utility and feasibility of candidate biomarkers in the clinic.

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Constellation Pharmaceuticals is an Equal Opportunity Employer, a participant in E-Verify and offers a comprehensive benefits package, including health, dental, 401(k), paid vacation, tuition reimbursement, and much more.

We are not accepting unsolicited resumes from employment agencies for any employment opportunities at this time.

Connect With Us

For inquiries or to request additional information we can be reached via:

Online Form Phone (617) 714-0555 Full Contact Info