Company Culture

Our employees are our single greatest asset. Our success lies in the hands of each individual in every corner of the company. We strive to create a work environment that is diverse, challenging, exciting, and fun. We believe that each team member has the ability to impact and improve the lives of those we work with, and those we work for—our patients.


Core Values

At Constellation, we believe in a set of core values that we put FIRST in everything that we do.


Each year, Constellation’s employees select two of their colleagues who most exemplify the company’s FIRST values.


We know what you will be bringing to our table, here is a glimpse of what we will bring to yours:

Bi-monthly Social Events + Fully Stocked Kitchens

Transit or Parking Reimbursements and Incentives

Medical, Dental + Vision Coverage and Deeply Discounted Gym Membership

Peer Nominated Awards + the Chance to Surround Yourself with some of Biotechs Best and BRIGHTEST

Professional Development, Education Assistance + Reimbursements for Memberships and Conferences

Wellness Incentives and In-Office Pop-Ups (yoga, meditation, walk/run clubs, group fitness)

401(k) Match + Equity

Flexible Time Off Policy, End of Year Company Shut Down

Paid Time Off for Volunteering

Join Us

Constellation Pharmaceuticals is a clinical-stage biopharmaceutical company using its expertise in epigenetics to discover and develop novel therapeutics.  Our employees are our single greatest asset. We know that our success lies in the hands of each individual in every corner of the company. We strive to create a work environment that is diverse, challenging, exciting, and fun. We believe that each team member has the ability to impact and improve the lives of those we work with, and those we work for—our patients.  We are #BrighterTogether.

We are looking for passionate employees that are eager to contribute to our stellar research, development, and business teams. If you are interested in applying or learning more about our current career opportunities please e-mail us at

Constellation is looking for a bright, energetic, and outgoing team member to manage forward facing IT operations while maintaining a white glove support model. As a key member of our IT team, representing end-user computing, you will offer informed opinions and weigh-in on IT decisions. If you enjoy a fast-paced environment that provides numerous challenges […]

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The Director of Drug Metabolism and Pharmacokinetics (DMPK) will be responsible for comprehensive DMPK support of all Discovery and Development programs. You will be a core member of the program teams providing DMPK perspectives and delivering on data that promote program progression and de-risk our assets. CNST is currently focused on small molecules as the […]

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We are seeking a Medical Director to oversee the design and implementation of multiple clinical development programs in support of the overall product development plan, based on strong medical and scientific principles, knowledge of compliance and regulatory requirements, their customers, markets, business operations, and emerging issues. The person in this role will oversee project-related education […]

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We are seeking an RA/Senior RA in Compound Management. This individual will be responsible for the execution of the day to day procedures supporting the business-critical function of compound management, helping to drive drug discovery for targets in the epigenetic field. We are #BrighterTogether.   How you will spend your day: Primary responsibilities include the […]

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The Functional Genomics group at Constellation seeks a highly motivated and enthusiastic Computational Biologist to be a part of an integrated computational/experimental biology team that identifies and validates novel oncology and immuno-oncology targets in the area of chromatin-mediated transcriptional regulation.  The ideal candidate will have a strong background in integrated NGS pipeline and data analysis, […]

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Reporting to the SVP Corporate Development, this newly created role will build the go-to-market strategy for Constellation’s lead pipeline program CPI-0610, with a first launch planned in myelofibrosis. We are #BrighterTogether   How you will spend your day: Re-shaping the therapeutic option landscape for patients living with MF Providing leadership across all aspects of plan […]

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The Director/Senior Director of Clinical Pharmacology will be responsible for developing, driving, and implementing (with internal collaborations and working with consultants/external partners) global Clinical Pharmacology strategies across multiple indications.  You will be a core member of the program teams providing Clinical Pharmacology perspectives and delivering modeling and analyses necessary to evaluate clinical options, enable plans, […]

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Reporting to the SVP Corporate Development, this newly created role will drive commercial strategy supporting Constellation pipeline development, with a near term focus on key decisions for our EZH2 Franchise asset development plans. We are #Brightertogether.   How you will spend your day? Providing commercial perspective to other pipeline asset development efforts as needed to support […]

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This position will provide support for several key functions in the company, including meeting coordination and calendaring, travel coordination, as well as general administrative assistance for the organization and the Human Resources team.  The successful candidate will be highly collaborative, creative, resourceful and self-motivated. They will embody our core values of being patient focused and […]

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The Principal Statistical Programmer will be responsible for implementing statistical analyses using SAS and performing quality review of SAS programs and deliverables for in-house analyses as well as out-sourced programming deliverables. This individual will also perform programming analyses to generate ad-hoc requests for manuscripts and presentations. This is an onsite position and reports to the […]

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The VP Finance is a well-rounded, experienced operational finance professional and will be responsible for oversight of the internal operations of the finance department in a small but growing public company.  Reporting to the CFO, this newly created position will work directly within a small, nimble finance group to provide oversight for both the financial […]

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We are looking for an experienced and motivated cancer biologist to join the Discovery Biology group at Constellation in order to help drive cutting-edge oncology drug discovery programs. You will report to the Head of Discovery Biology and be a key scientific leader supporting Constellation’s drug discovery programs. We are #BrighterTogether.   How you will […]

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The Head of Quality is a newly created position and will have the opportunity to define and build the Quality function at Constellation. This leader will work cross-functionally to create and maintain standards for GXP compliance and will have a high degree of impact across the organization. The Head of Quality will bring a proven […]

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This position is responsible for global safety assessment of investigational products throughout their lifecycle. This includes all pre-marketing safety, Pharmacovigilance and risk management (PVRM) activities. This individual will work together with the Sr. Director in managing the safety assessment of products, including review of individual and aggregate AEs and preparing safety reports. The ability to […]

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Don’t see the position you’re looking for? We want to hear from you regardless! Please submit your CV to us at

Constellation Pharmaceuticals recognizes the value of diversity in our workforce. We are committed to equal opportunity. We consider all qualified employment applicants without regard to race, religion, color, gender, age, national origin, sexual orientation, gender identity, partnership status, protected veteran status, disability, or any other status protected by federal, state, or local law. Individuals who hold legal work authorization applicable to employment at Constellation Pharmaceuticals in the United States will be considered without regard to citizenship/alienage. Constellation Pharmaceuticals is a participant in E-Verify.

We are not accepting unsolicited resumes from employment agencies for any employment opportunities at this time.