Senior Research Associate (SRA), or Research Investigator (RI) -- Lead Discovery, HTS

We are seeking a Senior Research Associate (SRA), or Research Investigator (RI) to work in a Lead Discovery group to support drug discovery efforts for various therapeutic targets in the epigenetic field.

Your primary responsibilities are to develop, optimize, validate and execute biochemical and cellular assays to support small molecule drug discovery projects, including assay development, automation, and running of screening assays, and characterization of small molecule leads in support of structure activity relationship studies.

This individual will be involved in all aspects of the screening process from compound management to reporting data. Additionally, you may also participate in protein purification procedures in order to supply enzymes and substrates for screening.

Basic Qualifications

• The position requires an enzymologist/biochemist with experience in biochemical and/or cell based assay development.

• The position requires HTS screening experience.

• A BS/MS degree in Biochemistry/Chemistry/Biology with 2 to 3 years industrial experience (SRA).

• Alternatively, qualifications could include a BS/MS degree in Biochemistry/Chemistry/Biology with
  8 years or more industrial experience (Research Investigator).

Preferred Qualifications

• An enzymologist with drug discovery experience is preferred.

• Experience with Mass Spectrometry for solving scientific problems is preferred.

• Experience with fluorescence based assay formats such as Homogeneous Time Resolved Fluorescence (HTRF), as well as radio labeled based assay formats such as Flashplate
  are preferred.